Colon & Crypt : Microscopic Anatomy

Drawings from the book by: Radivoj V. Krstic, Human Microscopic Anatomy. An atlas for students of medicine and biology. Springer-Verlag, Berlin, 1991.

See below drawings of the normal human colon, the normal mucosa, and normal crypts (closer and closer)
Some crypts can become aberrant, likely due to the mutation of a stem cell due to a carcinogen shot. Aberrant crypt can yield aberrant crypt focus (ACF) by crypt fission.

COLON (major part of large bowel or large intestine)
Surface of Colon TM: tunica mucosa TSm: tela submucosa TMu: tunica muscularis TSe: tunica serosa
Colonic Mucosa CL: crypts of Lieberkuhn E: epithelium GC: goblet cells Mu: mucus BL: basal lamina LP: lamina propria TM: tunica mucosa LMM: lamina muscularis- mucosae closer view