Chemoprevention of colon cancer: a systematic revue of preclinical studies.
Back to main page and database

Colon & Crypt : Microscopic Anatomy

Drawings from the book by: Radivoj V. Krstic, Human Microscopic Anatomy. An atlas for students of medicine and biology. Springer-Verlag, Berlin, 1991.

See below drawings of the normal human colon, the normal mucosa, and normal crypts down
Some crypts can become aberrant, likely due to the mutation of a stem cell due to a carcinogen shot. Aberrant crypt can yield aberrant crypt focus (ACF) by crypt fission.

(major part of
large bowel or
large intestine)


Crypt anatomy
(low quality, 100 ko)

Colonic Mucosa

CL: crypts
of Lieberkuhn
E: epithelium
GC: goblet cells
Mu: mucus
BL: basal lamina
LP: lamina propria
TM: tunica mucosa
LMM: lamina
muscularis- mucosae

Crypt anatomy (high definition, good quality, large size 999 ko)

Clik here to go back to main page
Très beaux dessins noir et blanc par R.V. Krstic de l'histologie du colon, et de la structure fine de cryptes de Lieberkühn

Corpet DE & Taché S, 2002, Nutrition & Cancer - & - DE Corpet & F Pierre, 2003, Cancer Epidemiol. Biomarkers Prevention
Chemoprevention database