TREATMENT dose | Author, year (click name for abstract) | No. tumor bearing rats Controls | Total no. of rats Controls | No. tumor bearing rats Treated | Total no. of rats Treated | RR | p | Potency on tumor incidence | Tumor percent inhibition | Protocol | Ro- dents | High Fat Low Fat diet | Carcinogen N x dose | weeks |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
wheat bran 20% LoFatChow NotBalanc. | Barbolt 78 | 23 | 40 | 18 | 40 | 0.78 | NS | 1.28 | 22 | both | Rs'" | L | dmh 10x22 | 22 |
wheat bran 15% vs 5%cell. HiFat | Watanabe 79 | 17 | 30 | 10 | 30 | 0.59 | MS | 1.70 | 42 | both | Rf | H | aom 10x8 | 40 |
wheat bran 15% vs 5%cell. HiFat//MNU | Watanabe 79 | 20 | 29 | 18 | 30 | 0.87 | NS | 1.15 | 13 | both | Rf | H | mnu 6x2 | 30 |
wheat bran 20% LoFatChow NotBalanc. | Barbolt 80 | 10 | 10 | 6 | 9 | 0.67 | NS | 1.50 | 33 | both | Rs' | L | dmh 10x30 | 22 |
wheat bran 15% vs 5%cell. LoFat aom | Reddy Mori 81 | 86 | 96 | 36 | 50 | 0.80 | * | 1.24 | 20 | both | Rf' | L | aom 10x8 | 30 |
wheat bran 15% vs 5%cell. LoFat dmab | Reddy Mori 81 | 43 | 94 | 13 | 50 | 0.57 | * | 1.76 | 43 | both | Rf' | L | dmab 20x50 | 40 |
wheat bran 20% vs 0%fibre LoFat | Jacobs 83 | 3 | 12 | 6 | 12 | 2.00 | NS | 0.50 | -100 | init | Rs' | L | dmh 13x20 | 31 |
wheat bran 20% vs 0%fibre LoFat | Jacobs 83 | 3- | 12- | 4 | 11 | 1.45 | NS | 0.69 | -45 | post | Rs' | L | dmh 13x20 | 31 |
wheat bran 20% vs 0%fibre LoFat | Jacobs 83 | 3- | 12- | 4 | 12 | 1.33 | NS | 0.75 | -33 | both | Rs' | L | dmh 13x20 | 31 |
wheat bran 15% vs 5%cell. HiFat&Cholic | Pence 86 | 25 | 60 | 21 | 60 | 0.84 | NS | 1.19 | 16 | both | Rf' | H | dmh 16x10 | 28 |
wheat bran 15% vs 5%cell. LoFat | Pence 86 | 2 | 20 | 8 | 20 | 4.00 | MS | 0.25 | -300 | both | Rf' | L | dmh 16x10 | 28 |
wheat bran 24% HiFat //MNNG | Sinkeldam 90 | 22 | 30 | 16 | 29 | 0.75 | NS | 1.33 | 25 | both | Rw' | H | mnng 5x6 | 33 |
wheat bran 20% MdFat //MNNG | Sinkeldam 90 | 18 | 30 | 12 | 30 | 0.67 | NS | 1.50 | 33 | both | Rw' | mnng 5x6 | 33 | |
wheat bran 17% LoFat //MNNG | Sinkeldam 90 | 12 | 30 | 13 | 30 | 1.08 | NS | 0.93 | -8 | both | Rw' | L | mnng 5x6 | 33 |
wheat bran 13% HiFat //MNNG | Sinkeldam 90 | 22- | 30- | 17 | 30 | 0.78 | NS | 1.28 | 22 | both | Rw' | H | mnng 5x6 | 33 |
wheat bran 12% MdFat //MNNG | Sinkeldam 90 | 18- | 30- | 24 | 30 | 1.33 | NS | 0.75 | -33 | both | Rw' | mnng 5x6 | 33 | |
wheat bran 09% LoFat //MNNG | Sinkeldam 90 | 12- | 30- | 18 | 30 | 1.50 | NS | 0.67 | -50 | both | Rw' | L | mnng 5x6 | 33 |
wheat bran 10% | Kritchevs. 97 | 16 | 23 | 10 | 24 | 0.60 | MS | 1.67 | 40 | post | Rf' | dmh 5x30 | 48 | |
wheat bran 20%microfibr./mice LoFat | Takahashi 99 | 18 | 19 | 18 | 19 | 1.00 | NS | 1.00 | both | Mf | L | aom 6x10 | 33 | |
wheat bran 16% HiFat | McIntosh 01 | 16 | 20 | 13 | 20 | 0.81 | NS | 1.23 | 19 | both | Rs' | H | aom 2x20 | 26 |
wheat bran 10% LoFat | Wijnands 04 | 24 | 26 | 22 | 29 | 0.83 | NS | 1.21 | 17 | both | Rf' | L | aom 3x15 | 35 |
Z | Refs.not included | 95%CI low | 95%CI high | |||||||||||
Z Total no. of rats / Global RR, p, 95%CI | Corpet & Pierre 05 | 355 | 569 | 307 | 595 | 0.83 | 0.0002 | 0.75 | 0.91 |
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